Abstract:Shandong Province is located in eastern China. It is controlled by structures and paleogeographical factors. Low mountainhilly landforms of Shandong Peninsula and central Shandong region has obvious differences with flat terrains of the North China Plain. This unique landform pattern and environmental characteristics have a significant impact on the distribution and evolution of regional mammals. Since the 20th century, multiple abundant mammalian fossil groups have been discovered in the Cenozoic strata of the central Shandong mountainous area and surrounding areas. Based on previous achievements, the fossil records of Cenozoic mammals in Shandong province have been studied, and the group composition of fossil producing areas have been summarized and statistically analyzed according to geological age. It is revealed that in the evolutionary process of the new generation of mammals, odd hooves, artiodactyls, rodents, and carnivores gradually occupy a dominant position. Odd hooves and artiodactyls improve their environmental adaptability by optimizing their motor functions, while rodents demonstrate outstanding reproductive strategy advantages. The population succession of different groups is significantly coupled with the evolution of regional ecological environment. It has reflected the dynamic response of mammals to changes in ancient environment and ecosystem reshaping. This research will provide crucial empirical data for analyzing the mechanisms of biodiversity evolution and reconstructing ancient environments.