Water inflow from poorly sealed boreholes is common in most mines. It is one of the main water hazards in mines. Taking Huibaoling iron deposit in southwestern Shandong province as the research object, through comprehensive analysis of hydrochemical characteristics (Durov diagram), water pressure (water level) and water volume, it is concluded that main water source for poorly sealed boreholes is fissure water in Liguan formation. Based on the characteristics of rock mechanics, a water prevention and control technology combining cutoff wall water stop, mid hole water stop and pressure relief, and segmented pressure relief grouting water stop has been proposed. It has achieved good water control effects and has reference significance for water stop work in poorly sealed boreholes in similar mines.