In order to achieve multipoint and highprecision monitoring of slope surface deformation, the use of unmanned aerial vehicle photography technology has been studied, and a measurement analysis model has been established through triangle intersection method to form spatial coordinate relationships. At the same time, by using accessory equipment accuracy correction mode, accuracy loss in drone photography in special environments has been reduced. It is showed that the monitoring of unmanned aerial vehicle shows high accuracy in the X and Y directions, while with relatively low accuracy in the Z direction. But only three points with an error will exceed 0.010m. Comparing with the monitoring results of the total stations, the data obtained from the monitoring of unmanned aerial vehicle is reliable. It can timely alert risks and prevent false alarms. It is more stable and efficient.