Caiyuan lead deposit is located in east of Anqiu and Gaomi lead metallogenic belts on both sides of the northern part of Yishu fault belt. On the basis of collecting and studying geophysical information of the similar deposits, geological characteristics, orecontrolling factors and the origin of deposit have been analyzed and studied. By using IP intermediate gradient method, combined profiles and high density electrical mehtod, exploration of lead deposit has gained a good effect, and geophysical prospecting signs have been summarized. It will provide important evidences for lead exploraiton in this area.